Inhibition of ADAM17 increases the cytotoxic effect of cisplatin in cervical spheroids and organoids
IntroductionCervical cancer represents one of the main causes of female, cancer-related mortality worldwide.The majority of cancers are caused by human papillomaviruses such as HPV16 and HPV18.As chemotherapeutic resistance to first-line platinum treatment is still a predominant clinical challenge in advanced cervical cancer, novel treatment option